| Related Knowledge Base Chapters|
|Antiretroviral Drugs Profiles|
Susa Coffey, MD.
|Metabolic Complications of HIV Therapy|
Dominic C. Chow, Larry J. Day, Scott A. Souza, Cecilia M. Shikuma, May 2006.
|Symptom Management Guidelines|
Lisa Capaldini, July 2004.
|Interactions of Antiretroviral Drugs: Related Resources|
|Adherence to HIV Antiretroviral Therapy|
Edward L. Machtinger, MD, David R. Bangsberg, MD, May 2005.
| Journal Articles|
|Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy: a systematic review and meta-analysis|
Shubber Z, Calmy A, Andrieux-Meyer I, Vitoria M, Renaud-Thery F, Shaffer N, Hargreaves S, Mills EJ, Ford N. AIDS. 2013 Jan 22. [Epub ahead of print]
|Systematic review of antiretroviral-associated lipodystrophy: lipoatrophy, but not central fat gain, is an antiretroviral adverse drug reaction|
de Waal R, Cohen K, Maartens G. PLoS One. 2013 May 28;8(5):e63623.
|Tolerability of HIV integrase inhibitors|
Lee FJ, Carr A. Curr Opin HIV AIDS. 2012 Sep;7(5):422-8. Review.
|Renal toxicity associated with antiretroviral therapy|
Calza L. HIV Clin Trials. 2012 Jul-Aug;13(4):189-211. Review.
|Liver toxicity of antiretroviral drugs|
Jones M, Núñez M. Semin Liver Dis. 2012 May;32(2):167-76. Review.
|Nucleoside reverse transcriptase inhibitor toxicity and mitochondrial DNA|
Koczor CA, Lewis W. Expert Opin Drug Metab Toxicol. 2010 Dec;6(12):1493-504. Review.
|A new era of antiretroviral drug toxicity|
Calmy A, Hirschel B, Cooper DA, et al. Antivir Ther. 2009;14(2):165-79. Review.
|Adverse effects of antiretrovirals in HIV-infected pregnant women|
Zuk DM, Hughes CA, Foisy MM, et al. Ann Pharmacother. 2009 Jun;43(6):1028-35.
|Neuropsychological functioning and antiretroviral treatment in HIV/AIDS: a review|
Cysique LA, Brew BJ. Neuropsychol Rev. 2009 Jun;19(2):169-85.
|The consequences of HIV infection and antiretroviral therapy use for cardiovascular disease risk: shifting paradigms|
Baker JV, Henry WK, Neaton JD. Curr Opin HIV AIDS. 2009 May;4(3):176-82.
|Adverse drug reactions to antiretroviral medication|
Roca B. Front Biosci (Landmark Ed). 2009 Jan 1;14:1785-92. Review.
|Adverse effects of antiretroviral therapy in HIV-1 infected children|
Shah I. J Trop Pediatr. 2006 Aug;52(4):244-8.
| Guidelines and Best Practices|
| Conference Reports and Proceedings|
| Online Books and Chapters|
| Newsletter Articles|
| Provider Education and Training|
|Adverse Effects and Comorbidities|
Clinical Care Options. A series of modules covering various topics relating to the prevention and management of side effects associated with the use of ARV medications. Updated regularly.
|Antiretroviral Rx: Adverse Effects|
HIV Web Study. 7 case-based learning modules for clinicians, from the Northwest AIDS Education and Training Center and the University of Washington. Updated regularly.
| Clinician Support Tools|
| Patient and Community Education|
|A Practical Guide to HIV Drug Side Effects|
Canadian AIDS Treatment Information Exchange (CATIE); 2012. A comprehensive online book for patients covering a wide variety of common ARV side effects. Also available in PDF format.
NAM-AIDSMAP; 2013. A patient-education booklet discussing possible adverse effects of ARV medications and how to manage them. Also available as an online flipbook.
A series of fact sheets for patients on side effects and how to deal with them, from aidsinfonet.org.
|Managing Side Effects of HIV Medications|
New York State Department of Health AIDS Institute; November 2006. An online educational booklet for patients.
|Side Effects of Anti-HIV Medications|
U.S. Department of Health and Human Services; October 2005. A series of fact sheets for patients on major side effects, including hepatotoxicity, hyperglycemia, hyperlipidemia, lactic acidosis, and skin rash.
|AIDSinfo Drug Database|
U.S. Department of Health and Human Services (DHHS) project providing information on antiretroviral treatment and drugs that treat or prevent AIDS-related illness.
Succinct, easy-to-read information on HIV drugs and related issues.
|Anti-HIV/OI/TB Therapeutics Database|
Computerized databases containing chemical structures and biological data established at the Division of AIDS (DAIDS) of NIAID to foster developments in the chemotherapy of HIV, opportunistic infections, and tuberculosis and to serve as an information source.
|Database of Antiretroviral Drug Interactions |
Search by antiretroviral drug, interacting drug, or interacting drug class. Maintained by HIV InSite.
Site features information on interactions with each class of antiretroviral drugs. Maintained by the Liverpool HIV Pharmacology Group, University of Liverpool.
|HIV Medication Guide|
Features information on single- and multiple-HIV drug interactions, a customizable medication chart function, patient drug pamphlets, and more. Available in English and French from JAG enterprises, a clinical pharmacy consultation firm.
|Johns Hopkins HIV Guide|
An on-line decision support tool designed to assist clinicians in the diagnosis, management and treatment of HIV/AIDS. Requires registration.
|NIAID/DAIDS: HIV/AIDS Treatment|
An easy-to-read site with a comprehensive overview of the discovery and development of AIDS therapeutics, from the Division of AIDS (DAIDS) of the National Institute of Allergy and Infectious Diseases (NIAID).
|Toronto General Hospital Immunodeficiency Clinic|
HIV treatment resources, including drug interactions tables, fact sheets, and other information for health care professionals.
Up-to-date, peer reviewed, clinically-relevant information on all U.S. drugs, as well as off-label uses and dosages, herbal supplements, nutritional products, and new and investigational drugs. Requires paid subscription.
|Cytochrome P450 Drug Interaction Table|
Designed as a hypothesis testing, teaching, and reference tool for physicians and researchers interested in drug interactions that are the result of competition for, or effects on the human cytochrome P450 system. Includes links to canned PubMed searches.
|FDA Center for Drug Evaluation and Research|
(CDER) Reports and information on prescription and over-the-counter drugs, as well as regulatory issues and the drug approval process, public health alerts, and more.
Physicians' Desk Reference online, featuring drug and healthcare information, with separate interfaces for physicians, pharmacists, physician assistants, nurses, and consumers. Registration is required, and is either free or fee-based, depending on the level of access desired.
Index of information on pharmaceutical products from WebMD. Features search function for looking up drugs by the pill imprint code, color, or shape.
| Adverse Event Reporting and Emergencies|
|American Association of Poison Control Centers|
List of poison control centers.
|Antiretroviral Pregnancy Registry|
Intended to provide an early signal of any major teratogenic effect associated with a prenatal exposure to the products monitored through the registry, a voluntary prospective, exposure-registration, observational study designed to collect and evaluate data on the outcomes of pregnancy exposures to antiretroviral products.
FDA safety information and adverse event reporting program for drugs and other medical products.
|U.S. Pharmacopeial Convention|
A scientific nonprofit organization that sets standards for the identity, strength, quality, and purity of medicines, food ingredients, and dietary supplements manufactured, distributed and consumed worldwide.
|Vaccine Adverse Event Reporting System|
(VAERS) Vaccine surveillance program of the FDA Center for Biologics Evaluation and Research.