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Diagnosis and Management of Primary (Acute) HIV Infection: Related Resources
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arrow imageUpdates
arrow imageJournal Articles
arrow imageGuidelines and Best Practices
arrow imagePolicy Reports, Papers, and Briefs
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Updates
AIDS 2012: French Cohort Treated during Primary Infection Appears to Control HIV without ART
HIVandHepatitis.com. August 8, 2012.
Journal Articles
Diagnosing HIV infection in primary care settings: missed opportunities
Chin T, Hicks C, Samsa G, McKellar M. AIDS Patient Care STDS. 2013 Jul;27(7):392-7.
Laboratory diagnosis of HIV in adults: a review of current methods
Cornett JK, Kirn TJ. Clin Infect Dis. 2013 Jun 13. [Epub ahead of print]
Acute human immunodeficiency virus infection
Richey LE, Halperin J. Am J Med Sci. 2013 Feb;345(2):136-42. Review.
Short-course antiretroviral therapy in primary HIV infection
SPARTAC Trial Investigators, Fidler S, Porter K, et al. N Engl J Med. 2013 Jan 17;368(3):207-17.
Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy
Le T, Wright EJ, Smith DM, et al. N Engl J Med. 2013 Jan 17;368(3):218-30.
Should we treat acute HIV infection?
O'Brien M, Markowitz M. Curr HIV/AIDS Rep. 2012 Jun;9(2):101-10. Review.
Testing for acute HIV infection: implications for treatment as prevention
Owen SM. Curr Opin HIV AIDS. 2012 Mar;7(2):125-30. Review.
Diagnosing acute HIV infection
Yerly S, Hirschel B. Expert Rev Anti Infect Ther. 2012 Jan;10(1):31-41. Review.
The acute HIV infection: implications for intervention, prevention and development of an effective AIDS vaccine
Nishimura Y, Martin MA. Curr Opin Virol. 2011 Sep;1(3):204-10. Review.
Acute HIV infection
Cohen MS, Shaw GM, McMichael AJ, Haynes BF. N Engl J Med. 2011 May 19;364(20):1943-54. Review.
Diagnosis and initial management of acute HIV infection
Chu C, Selwyn PA. Am Fam Physician. 2010 May 15;81(10):1239-44. Review.
High rates of forward transmission events after acute/early HIV-1 infection
Brenner BG, Roger M, Routy JP, et al; Quebec Primary HIV Infection Study Group. J Infect Dis. 2007 Apr 1;195(7):951-9.
Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection
Hare CB, Pappalardo BL, Busch MP, Karlsson AC, wt al. Clin Infect Dis. 2006 Mar 1;42(5):700-8.
Guidelines and Best Practices
Considerations for Antiretroviral Use in Special Patient Populations: Acute and Recent (Early) HIV Infection
U.S. Department of Health and Human Services; Panel on Antiretroviral Guidelines for Adults and Adolescents.

Excerpt from the current version of the Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents.

Diagnosis and Management of Acute HIV Infection
New York State Department of Health AIDS Institute; January 2010.
Policy Reports, Papers, and Briefs
Detection of Acute HIV Infection in Two Evaluations of a New HIV Diagnostic Testing Algorithm--United States, 2011-2013
U.S. Centers for Disease Control and Prevention. MMWR 62(24);489-494. June 21, 2013.
Online Books and Chapters
Primary HIV Infection Chapter: Guide for HIV/AIDS Clinical Care
AIDS Education and Training Centers National Resource Center, 2014.
Acute HIV-1 Infection
Marcus Altfeld, Bruce D. Walker. In: HIV Medicine, Flying Publisher, 2006.
Clinician Support Tools
Acute HIV Infection Quick Reference
Mountain Plains AETC; January 2012.

Pocket guide covering risk assessment, common signs and symptoms of acute HIV infection, as well as testing, referral, and treatment considerations. The guide also includes clinical images of acute HIV infection and resources. (5" x 5").

HIVMA Guide to Recognizing Acute Infection
HIV Medicine Association (HIVMA), July 2006.
Learn to Recognize Acute HIV Syndrome: Wall Chart
New York/New Jersey AIDS Education and Training Center, 2004. [PDF, 507K]
Slide Sets
Diagnosis and Management of Acute HIV Infection
New York State Department of Health AIDS Institute; January 2010. [PPT, 180K]

A slide set to accompany the New York state HIV clinical guidelines.

Patient and Community Education
What Is the Role of Acute HIV Infection in HIV Prevention?
UCSF Center for AIDS Prevention Studies (CAPS), January 2006.
Treatment During Primary Infection
Aidsmap. Updated periodically.
Primary Infection
Aidsmap. Updated periodically.
Links
The Acute HIV Infection Disease Research Program at Massachusetts General Hospital
website provides information for HIV researchers, patients, and their providers about the earliest events during HIV infection and the importance of these events in subsequent disease progression.
The Acute Infection and Early Disease Research Program (AIEDRP)
AIEDRP conducts research into early HIV infection and how early treatment may or may not affect disease progression later. AIEDRP is a multisite study funded by the National Institute of Allergy and Infectious Diseases.
UCSF OPTIONS Project
The OPTIONS Project is a San Francisco-based research study sponsored by UCSF. The goal of the OPTIONS Project is to learn as much as possible about early HIV infection and how transmission of HIV occurs.