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Structure, Expression, and Regulation of the HIV Genome: Related Resources
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Related Knowledge Base Chapters
Molecular Insights Into HIV Biology
Warner C. Greene, B. Matija Peterlin, February 2003.
Journal Articles
Inhibitors of HIV-1 entry and integration: recent developments and impact on treatment
Sharma AK, George V, Valiathan R, et al. Recent Pat Inflamm Allergy Drug Discov. 2013 May 1;7(2):151-61.
HIV-1 dynamics: a reappraisal of host and viral factors, as well as methodological issues
Prentice HA, Tang J. Viruses. 2012 Oct 10;4(10):2080-96.
The biased nucleotide composition of the HIV genome: a constant factor in a highly variable virus
van der Kuyl AC, Berkhout B. Retrovirology. 2012 Nov 6;9:92.
Human immunodeficiency virus reverse transcriptase: 25 years of research, drug discovery, and promise
Le Grice SF. J Biol Chem. 2012 Nov 30;287(49):40850-7.
New horizons for antiviral drug discovery from virus-host protein interaction networks
de Chassey B, Meyniel-Schicklin L, Aublin-Gex A, et al. Curr Opin Virol. 2012 Oct;2(5):606-13.
Genome-wide association studies on HIV susceptibility, pathogenesis and pharmacogenomics
van Manen D, van 't Wout AB, Schuitemaker H. Retrovirology. 2012 Aug 24;9:70.
The origin of genetic diversity in HIV-1
Smyth RP, Davenport MP, Mak J. Virus Res. 2012 Nov;169(2):415-29.
Mutational analysis of the HIV-1 auxiliary protein VIF identifies independent domains important for the physical and functional interaction with HIV-1 reverse transcriptase
Kataropoulou A, Bovolenta C, Belfiore A, et al. Nucleic Acids Research. 2009 Jun; 37(11): 3660 - 3669.
Dynamic binding orientations direct activity of HIV reverse transcriptase
Abbondanzieri E, Bokinsky G, Rausch J. Nature. 2008 May 8; 453: 184-189.
Conference Reports and Proceedings
Basic Science Summary
Mario Stevenson. Topics in Antiviral Medicine, International Antiviral Society-USA; April/May 2013. Highlights of the 20th Conference on Retroviruses and Opportunistic Infections; Atlanta; March 3-6, 2013. [PDF, 124K]
Presentations, Interviews, and Roundtable Discussions
Molecular Biology of HIV-1: Regulatory Genes
Gatignol A, McGill University; March 2007. [PDF]
HIV Life Cycle - Animations:
bullet.gifThe Life Cycle of HIV, a Retrovirus
Perry, et al., Microbial Life, First Edition. 2002. [Adobe Flash]
Created by Jim Sullivan.
HIV and Antiretroviral Drugs - Animations:
bullet.gifAnti-HIV Therapy
Bless Castro, PhD, and Laurence Peiperl, MD. The structure, life cycle, and pathogenesis of HIV, and the function of antiretroviral drugs. Animated Flash educational course with audio, produced by GeneEd and HIV InSite. Full running time is 30 minutes, but course may also be viewed in sections.
Online Books and Chapters
HIV Sequence Compendium 2012
Kuiken C, Foley B, Marx P, et al. Published by Theoretical Biology and Biophysics, Los Alamos National Laboratory, LA-UR 09-03280. [PDF]
John M. Coffin, Stephen H. Hughes, Harold E. Varmus, Cold Spring Harbor Laboratory Press; c1997.
Human immunodeficiency virus 1, complete genome
NCBI Viral Genomes; Completed: Dec 23, 2003.
Human immunodeficiency virus 2, complete genome
NCBI Viral Genomes; Completed: Jul 17, 2002.
Electron Micrograph and Diagrams of Structural Components of Human Immunodeficiency Virus
The Internet Pathology Laboratory for Medical Education.