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Metabolic Complications of HIV Therapy: Related Resources
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Related Knowledge Base Chapters
decorative spacerOverview of Antiretroviral Drugs
Laurence Peiperl, Susa Coffey
decorative spacerHIV-Associated Wasting
Kathleen Mulligan, Morris Schambelan, November 2003.
decorative spacerSide Effects of Antiretroviral Drugs: Related Resources
Journal Articles
decorative spacerMetabolic complications and treatment of perinatally HIV-infected children and adolescents
Barlow-Mosha L, Eckard AR, McComsey GA, et al. J Int AIDS Soc. 2013 Jun 18;16:18600.
decorative spacerPredicting the short-term risk of diabetes in HIV-positive patients: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study
Petoumenos K, Worm SW, Fontas E, et al; D:A:D Study Group. J Int AIDS Soc. 2012 Oct 10;15(2):17426.
decorative spacerBody composition and metabolic changes in HIV-infected patients
Stanley TL, Grinspoon SK. J Infect Dis. 2012 Jun;205 Suppl 3:S383-90. Review.
decorative spacerHIV medications: an update and review of metabolic complications
Hester EK. Nutr Clin Pract. 2012 Feb;27(1):51-64. Review.
decorative spacerSevere malnutrition and metabolic complications of HIV-infected children in the antiretroviral era: clinical care and management in resource-limited settings
Musoke PM, Fergusson P. Am J Clin Nutr. 2011 Dec;94(6):1716S-1720S. Review.
decorative spacerManagement of the metabolic effects of HIV and HIV drugs
Brown TT, Glesby MJ. Nat Rev Endocrinol. 2011 Sep 20;8(1):11-21. Review.
decorative spacerThe prevalence and pathogenesis of diabetes mellitus in treated HIV-infection
Paik IJ, Kotler DP. Best Pract Res Clin Endocrinol Metab. 2011 Jun;25(3):469-78. Review.
decorative spacerHIV infection, body composition changes and related metabolic complications: contributing factors and evolving management strategies
Falutz J. Curr Opin Clin Nutr Metab Care. 2011 May;14(3):255-60. Review.
decorative spacerDyslipidemia and its treatment in HIV infection
Grunfeld C. Top HIV Med. 2010 Aug-Sep;18(3):112-8. Review.
decorative spacerSwitching antiretroviral therapy to minimize metabolic complications
Lake JE, Currier JS. HIV Ther. 2010 Nov;4(6):693-711.
decorative spacerMetabolic outcomes in a randomized trial of nucleoside, nonnucleoside and protease inhibitor-sparing regimens for initial HIV treatment
Haubrich RH, Riddler SA, DiRienzo AG, et al; AIDS Clinical Trials Group (ACTG) A5142 Study Team. AIDS. 2009 Jun 1;23(9):1109-18.
decorative spacerIntegrating Nutrition Therapy into Medical Management of Human Immunodeficiency Virus
Clinical Infectious Diseases (supplement), April 1, 2003. Special issue of CID, with articles devoted to HIV-related nutritional issues and metabolic abnormalities.
Guidelines and Best Practices
decorative spacer Management of Metabolic Complications Associated with Antiretroviral Therapy for HIV-1 InfectionRecommendations of an International AIDS Society-USA Panel, JAIDS, November 1, 2002.
Conference Reports and Proceedings
decorative spacerComplications of HIV Disease, Viral Hepatitis, and Antiretroviral Therapy
Anne F. Luetkemeyer, Diane V. Havlir, Judith S. Currier. Topics in Antiviral Medicine, International Antiviral Society-USA, April/May 2013. Highlights of the 20th Conference on Retroviruses and Opportunistic Infections; Atlanta; March 3-6, 2013. [PDF, 531K]
Presentations, Interviews, and Roundtable Discussions
decorative spacerMetabolic Complications of HIV (and Antiretroviral Therapy)
New York State Department of Health AIDS Institute, Clinical Education Initiative; November 2012.

An online video learning module presented by Dr. Marshall Glesby, MD, PhD.

decorative spacerCo-Morbidities and Metabolic Complications in HIV
A 20-minute video presentation of a panel discussion at the 19th Conference on Retroviruses and Opportunistic Infections; March 5-8, 2012; Seattle. Panelists include Michael Dubé, MD; Edgar Turner Overton, MD; David Alain Wohl, MD; and Ronald T. Mitsuyasu, MD. Moderated by Jeff Taylor. From the website.
decorative spacerMetabolic Complications and Aging in HIV
New England AIDS Education and Training Center; September 2011. [PDF, 2.73MB]

A presentation given by Steven Grinspoon, MD, at the 6th National Conference on HIV/AIDS and Aging Symposium in Boston.

Online Books and Chapters
decorative spacerA Helpful Guide to HIV and Metabolic Complications
U.S. Department of Health and Human Services, National Institute of Allergy and Infectious Diseases. December 2007. [PDF, 645K]
decorative spacerAbnormalities of Body-Fat Distribution Chapter: Guide for HIV/AIDS Clinical Care
AIDS Education and Training Centers National Resource Center, 2014.
Provider Education and Training
decorative spacerMetabolic Complications Associated with the Treatment of HIV-Infected Persons
Fussa MJ, Paul Sindy M; Rutgers University Center for Continuing and Outreach Education; June 2008. An online learning activity designed for physicians, nurses, and other health care professionals involved in the care of persons with HIV/AIDS. Also available in PDF format.
Slide Sets
decorative spacerMetabolic Complications of HIV
Haelel L; New York/New Jersey AETC; December 2010. [PowerPoint, 2.25MB]
decorative spacerMetabolic Complications of HIV Infection and Antiretroviral Therapy
Northwest AETC; 2006. [PowerPoint, 9.5MB]
decorative spacerAIDSinfo Drug Database
U.S. Department of Health and Human Services (DHHS) project providing information on antiretroviral treatment and drugs that treat or prevent AIDS-related illness.
Succinct, easy-to-read information on HIV drugs and related issues.
decorative spacerAnti-HIV/OI/TB Therapeutics Database
Computerized databases containing chemical structures and biological data established at the Division of AIDS (DAIDS) of NIAID to foster developments in the chemotherapy of HIV, opportunistic infections, and tuberculosis and to serve as an information source.
decorative spacerDatabase of Antiretroviral Drug Interactions
Search by antiretroviral drug, interacting drug, or interacting drug class. Maintained by HIV InSite.
Site features information on interactions with each class of antiretroviral drugs. Maintained by the Liverpool HIV Pharmacology Group, University of Liverpool.
decorative spacerHIV Medication Guide
Features information on single- and multiple-HIV drug interactions, a customizable medication chart function, patient drug pamphlets, and more. Available in English and French from JAG enterprises, a clinical pharmacy consultation firm.
decorative spacerJohns Hopkins HIV Guide
An on-line decision support tool designed to assist clinicians in the diagnosis, management and treatment of HIV/AIDS. Requires registration.
decorative spacerNIAID/DAIDS: HIV/AIDS Treatment
An easy-to-read site with a comprehensive overview of the discovery and development of AIDS therapeutics, from the Division of AIDS (DAIDS) of the National Institute of Allergy and Infectious Diseases (NIAID).
decorative spacerToronto General Hospital Immunodeficiency Clinic
HIV treatment resources, including drug interactions tables, fact sheets, and other information for health care professionals.
decorative spacerClinical Pharmacology
Up-to-date, peer reviewed, clinically-relevant information on all U.S. drugs, as well as off-label uses and dosages, herbal supplements, nutritional products, and new and investigational drugs. Requires paid subscription.
decorative spacerCytochrome P450 Drug Interaction Table
Designed as a hypothesis testing, teaching, and reference tool for physicians and researchers interested in drug interactions that are the result of competition for, or effects on the human cytochrome P450 system. Includes links to canned PubMed searches.
decorative spacerFDA Center for Drug Evaluation and Research
(CDER) Reports and information on prescription and over-the-counter drugs, as well as regulatory issues and the drug approval process, public health alerts, and more.
Physicians' Desk Reference online, featuring drug and healthcare information, with separate interfaces for physicians, pharmacists, physician assistants, nurses, and consumers. Registration is required, and is either free or fee-based, depending on the level of access desired.
decorative spacerRxList
Index of information on pharmaceutical products from WebMD. Features search function for looking up drugs by the pill imprint code, color, or shape.
Adverse Event Reporting and Emergencies
decorative spacerAmerican Association of Poison Control Centers
List of poison control centers.
decorative spacerAntiretroviral Pregnancy Registry
Intended to provide an early signal of any major teratogenic effect associated with a prenatal exposure to the products monitored through the registry, a voluntary prospective, exposure-registration, observational study designed to collect and evaluate data on the outcomes of pregnancy exposures to antiretroviral products.
decorative spacerMedWatch
FDA safety information and adverse event reporting program for drugs and other medical products.
decorative spacerU.S. Pharmacopeial Convention
A scientific nonprofit organization that sets standards for the identity, strength, quality, and purity of medicines, food ingredients, and dietary supplements manufactured, distributed and consumed worldwide.
decorative spacerVaccine Adverse Event Reporting System
(VAERS) Vaccine surveillance program of the FDA Center for Biologics Evaluation and Research.