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HIV in Indiana
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This article describes the CDC investigation and response (through October 2015) to the ongoing HIV (and HCV) outbreak in a rural county in Indiana, centered in people who inject opiates (especially the prescription drug Opana [oxymorphone]). The outbreak was first recognized in 2015 and continues to spiral onward--there are now >200 cases. The study is well presented, and it touches on failures of prevention including factors such as (lack of) access to syringe exchange services, poverty, and health insurance status, not to mention lack of access to drug treatment programs.

Peters PJ, Pontones P, Hoover KW, et al; Indiana HIV Outbreak Investigation Team. HIV infection linked to injection use of oxymorphone in Indiana, 2014-2015. N Engl J Med. 2016 Jul 21;375(3):229-39.