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Database of Antiretroviral Drug Interactions

Interactions with Avanafil and Antiretrovirals

Antiretroviral (ARV)Dose of ARVDose of AvanafilEffect on ARV LevelsEffect on Avanafil LevelsPotential Clinical EffectsMechanism of InteractionManagement
Elvitegravir/cobicistat727
(Genvoya, Stribild)
-- No effect expectedNot studied; may increase avanafil levels --

Avoid coadministration

Elvitegravir/ritonavir-boosted protease inhibitor727
-- No effect expected Not studied; may increase avanafil levels --

Avoid coadministration

"-" indicates that there are no data available
 727:Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. Available at http://aidsinfo.nih.gov/contentfiles/lvguidelines/AdultandAdolescentGL.pdf.