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Home > Treatment > Drug Dosing Toolkit > Viread

tenofovir disoproxyl fumarate, TDF (Viread)

Type of Drug: Nucleotide Reverse Transcriptase Inhibitor

Nucleotide reverse transcriptase inhibitors are also known as NRTIs, nucleotide analogues, or "nukes."

When the HIV virus enters a healthy cell, it attempts to make copies of itself. It does this by using an enzyme called reverse transcriptase. NRTIs block that enzyme, so HIV cannot make new copies of itself.

Approved adult dosing

one 300 mg tablet, once a day

  • Once daily

    Viread 300


Notes on taking this medication

  • No food restrictions, can take with or without food
  • Persons with kidney problems may need an adjustment to their dosing schedule, or may need a different drug

Possible side effects

  • Gassiness; abdominal discomfort; nausea; diarrhea
  • Kidney impairment
  • Bone impairment
  • Viread is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

Scroll over drug name to see other names for the drug.