(didanosine, ddI EC)
- Type of Drug: Nucleoside Reverse Transcriptase Inhibitor
Nucleoside reverse transcriptase inhibitors were the first type of drug available to treat HIV. They are also known as NRTIs, nucleoside analogues, or "nukes."
When the HIV virus enters a healthy cell, it attempts to make copies of itself. It does this by using an enzyme called reverse transcriptase. NRTIs block that enzyme, so HIV cannot make new copies of itself.
Approved adult dosing
one 400 mg capsule, once a day
Videx EC 400 mg
If under 133 pounds:
one 250 mg capsule, once a day
Videx EC 250 mg
Note: Generic formulations are available; these generic pills may have different shapes and colors than the ones shown above.
Notes on taking this medication
- Dose may need to be adjusted because Videx EC can interact with other HIV drugs; dose should be reduced to 250 mg once a day if taken with Viread, Truvada, or Atripla
- Take on empty stomach 2 hours after or 1 hour before meal (if taken with Viread, there are no food restrictions)
- Persons with kidney problems may need an adjustment to their dose of Videx EC
- Numbness, tingling, or pain in the hands and feet (peripheral neuropathy)
- Nausea; vomiting; diarrhea; abdominal pain
- Changes in body-fat distribution, especially fat loss
See accompanying chart: Tips for Common Side Effects
My doctor's instructions
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