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Triumeq (Tivicay + Epivir + Ziagen)

Type of Drug: Fixed-Dose Combination
Fixed-dose combinations combine the most commonly prescribed doses of 2 or more medications into a single pill.

Approved adult dosing

Tivicay 50 mg + Epivir 300 mg + Abacavir 600 mg in a single tablet

  • Daily



Notes on taking this medication

  • No food restrictions; you can take Triumeq with or without food.
  • Before taking Triumeq, you should be tested to see if you are at risk of a serious allergic reaction to the Ziagen component. The test is a blood test for a genetic marker called HLA B5701.
  • Do not take if you are positive for HLA B5701 or allergic to abacavir (Ziagen). Tell your pharmacist if your provider tells you that you are "allergic" to Epzicom or Ziagen.
  • Triumeq can interact with other drugs; consult your medical provider.
  • Antacids, laxatives, mineral supplements, and other compounds that contain calcium, magnesium, aluminum, or iron can decrease levels of Tivicay if they are taken close in time to each other. Ask your provider whether or how you can take these compounds with Tivicay.
  • Persons with kidney problems may need an adjustment to their doses of the component drugs, and have to take them separately, not as a single pill.

Side effects

  • Triumeq has not been studied during pregnancy; tell your medical provider if you become pregnant while taking this drug

See accompanying chart: Tips for Common Side Effects

Same side effects as


  • Usually well tolerated; may cause nausea; sleep disturbance; headache; muscle aches; rash


  • Side effects are rare but include headaches and general sense of feeling ill
  • Epivir is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B


  • Mild nausea; vomiting; diarrhea; loss of appetite
  • Rash
  • Hypersensitivity reaction

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

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