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Home > Treatment > Drug Dosing Toolkit > Invirase

Invirase (saquinavir)

Type of Drug: Protease Inhibitor
Once HIV has infected a cell and made copies of itself, it uses an enzyme called protease to process itself correctly so it can be released from the cell to infect other cells. Protease inhibitors work by blocking that enzyme.
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Approved adult dosing

two 500 mg tablets Invirase + one 100 mg tablet or capsule Norvir, two times a day

  • Morning

    Invirase 500Invirase 500

    Invirase 500 mg

    +
    Norvir 100

    Norvir

  • Evening

    Invirase 500Invirase 500

    Invirase 500 mg

    +
    Norvir 100

    Norvir

five 200 mg capsules Invirase + one 100 mg tablet or capsule Norvir, two times a day

  • Morning

    Invirase 200Invirase 200Invirase 200Invirase 200Invirase 200

    Invirase 200 mg

    +
    Norvir 100

    Norvir

  • Evening

    Invirase 200Invirase 200Invirase 200Invirase 200Invirase 200

    Invirase 200 mg

    +
    Norvir 100

    Norvir

Notes on taking this medication

  • Take with food or after a meal
  • Invirase interacts with many other drugs; persons using Invirase with those drugs may need an adjustment to their dose of Invirase or the other drugs; consult your medical provider

Side effects

  • Nausea; vomiting; diarrhea; stomach discomfort; headache
  • Liver inflammation and increased liver enzyme levels
  • Elevations in cholesterol and triglycerides
  • Abnormal accumulation of body fat

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

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