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Home > Treatment > Drug Dosing Toolkit > Evotaz

Reyataz + Tybost (Evotaz)

Type of Drug: Fixed-Dose Combination
Fixed-dose combinations combine the most commonly prescribed doses of 2 or more medications into a single pill.

Approved adult dosing

Reyataz 300 mg + Tybost 150 mg in a single tablet

one tablet, once a day

  • Once daily



Notes on taking this medication

  • Should take with food
  • Evotaz interacts with many other drugs; persons using Evotaz with those drugs may need an adjustment to their dose of Evotaz or the other drugs; consult your medical provider
  • Medicines for indigestion, heartburn, and ulcers (including medicines available over the counter) may block the body's absorption of Evotaz; check with your medical provider before using these medicines

Same possible side effects as


  • Jaundice (yellow eyes and/or yellow skin), especially when used with Norvir; this is rarely serious, but let your medical provider know if this develops
  • Abdominal pain; liver inflammation and increased liver enzyme levels
  • Uncommon: elevations in cholesterol and triglycerides, kidney stones, gallstones


  • Nausea, diarrhea
  • Headache, fatigue
  • Elevation in blood creatinine levels (this is used to assess kidney function; your provider will monitor creatinine)

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

Scroll over drug name to see other names for the drug.