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Home > Treatment > Drug Dosing Toolkit > Combivir

AZT + Epivir (Combivir)

Type of Drug: Fixed-Dose Combination

Fixed-dose combinations combine the most commonly prescribed doses of more than 1 medication into a single pill.

Approved adult dosing

AZT 300 mg + Epivir 150 mg in a single tablet

one tablet , two times a day

  • Morning



  • Evening



Note: Generic formulations are available; these generic pills may have different shapes and colors than the one shown above.

Notes on taking this medication

  • No food restrictions, can take with or without food
  • Do not take Combivir with Emtriva or Zerit
  • Persons with kidney problems may need an adjustment to their doses of the component drugs, so may not be able to take this combination pill

Same possible side effects as

AZT (Retrovir)

  • Nausea; stomach discomfort; headache
  • Symptoms of anemia (low red blood cell count): fatigue; shortness of breath
  • More rarely: muscle wasting; neutropenia (low white blood cell count)
  • Changes in body-fat distribution


  • Side effects are rare but include headaches and general sense of feeling ill
  • Epivir is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

Scroll over drug name to see other names for the drug.