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Adherence to HIV Antiretroviral Therapy: Related Resources
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Related Knowledge Base Chapters
Antiretroviral Drug Profiles
Laurence Peiperl, Susa Coffey.
Symptom Management Guidelines
Lisa Capaldini, July 2004.
Genotypic Testing for HIV Drug Resistance
Robert W. Shafer, April 2004.
Side Effects of Antiretroviral Drugs: Related Resources
Journal Articles
Mobile phone technologies improve adherence to antiretroviral treatment in a resource-limited setting: a randomized controlled trial of text message reminders
Pop-Eleches C, Thirumurthy H, Habyarimana JP, Zivin JG, Goldstein MP, de Walque D, Mackeen L, Haberer J, Kimaiyo S, Sidle J, Ngare D, Bangsberg DR. AIDS. 2011 February 10. [Epub ahead of print] Includes commentary from the UCSF Institute for Global Health.
Risk of viral failure declines with duration of suppression of highly active antiretroviral therapy irrespective of adherence level
Lima VD, Bangsberg DR, Harringan PR, et al. JAIDS. 2010 Dec 1;55(4):460-5. Includes commentary from the UCSF Institute for Global Health.
Entry and retention in medical care among HIV-diagnosed persons: a meta-analysis
Marks G, Gardner LI, Craw J, Crepaz N. AIDS. 2010 Nov 13; 24(17):2665-78. Includes commentary from the UCSF Institute for Global Health.
Trends in retention on antiretroviral therapy in national programs in low-income and middle-income countries
Tassie JM, Baijal P, Vitoria MA, et al. J Acquir Immune Defic Syndr. 2010 Aug 1;54(4):437-41. Includes commentary from the UCSF Institute for Global Health.
Understanding reasons for and outcomes of patients lost to follow-up in antiretroviral therapy programs in Africa through a sampling-based approach
Geng EH, Bangsberg DR, Musinguzi N. J Acquir Immune Defic Syndr. 2009 Sep 10. Includes commentary from the UCSF Institute for Global Health.
HIV-1 viral load monitoring: an opportunity to reinforce treatment adherence in a resource-limited setting in Thailand
Wilson D, Keiluhu AK, Kogrum S, et al. Trans R Soc Trop Med Hyg. 2009;103(6):601-6. Includes commentary from the UCSF Institute for Global Health.
Implementation of a comprehensive program including psycho-social and treatment literacy activities to improve adherence to HIV care and treatment for a pediatric population in Kenya
Van Winghem J, Telfer B, Reid T, et al. BMC Pediatr. 2008 Nov 21;8:52. Includes commentary from the UCSF Institute for Global Health.
Adherence support workers: A way to address human resource constraints in antiretroviral treatment programs in the public health setting in Zambia
Torpey K, Mushota E, Mutale LN, et al. PLoS ONE. 2008;3(5):e2204. Includes commentary from the UCSF Institute for Global Health.
Short- and long-term efficacy of modified directly observed antiretroviral treatment Mombasa, Kenya: A randomized trial
Sarna A, Luchters S, Giebel S, et al. J Acquir Immune Defic Syndr. 2008;48:611-19. Includes commentary from the UCSF Institute for Global Health.
Evaluating adherence to highly active antiretroviral therapy with use of pill counts and viral load measurement in the drug resources enhancement against AIDS and malnutrition program in Mozambique
San Lio MM, Carbini R, Germano P, et al. Clin Infect Dis. 2008 May15;46(10):1609-16. Includes commentary from the UCSF Institute for Global Health.
Explaining adherence success in Sub-Saharan Africa: an ethnographic study
Norma C. Ware, John Idoko, Sylvia Kaaya, et al. PLoS Medicine. 2009; 6 (1):39-47.
Adherence to antiretroviral therapy assessed by drug level monitoring and self-report in Cameroon
Kouanfack C, Laurent C, Peytavin G, Ciaffi L, Ngolle M, Mawamba Y, et al. J Acquir Immune Defic Syndr. 2008;48:216-19. Includes commentary from the UCSF Institute for Global Health.
Electronic measurement of adherence to pediatric antiretroviral therapy in South Africa
Muller A, Bode S, Myer L, Roux P, von Steinbuchel N. AIDS 2008;27:257-62. Includes commentary from the UCSF Institute for Global Health.
Characteristics and outcomes of adult patients lost to follow-up at an antiretroviral treatment clinic in Johannesburg, South Africa
Dalal RP, MacPhail C, Mqhayi M, Wing J, Feldman C, Chersich MF, et al. J Acquir Immune Defic Syndr 2008 Jan 1;47(1):101-7. Includes commentary from the UCSF Institute for Global Health.
Adherence to antiretroviral therapy in patients receiving free treatment from a government hospital in Blantyre, Malawi
Bell DJ, Kapitao Y, Sikwese R, van Oosterhout JJ, Lalloo DG. J Acquir Immune Defic Syndr 2007 Aug 15;45(5):560-3. Includes commentary from the UCSF Institute for Global Health.
Predictors of failure of first-line antiretroviral therapy in HIV-infected adults: Indian experience
Rajasekaran S, Jeyaseelan L, Vijila S, Gomathi C, Raja K. AIDS 2007 Jul;21 Suppl 4:S47-53. Includes commentary from the UCSF Institute for Global Health.
Sustained Benefit from a Long-Term Antiretroviral Adherence Intervention: Results of a Large Randomized Clinical Trial
Mannheimer SB, Morse E, Matts JP, Andrews L, Child C, Schmetter B, Friedland GH; Terry Beirn Community Programs for Clinical Research on AIDS. J Acquir Immune Defic Syndr. 2006 Dec 1;43 Suppl 1:S41-7. Includes commentary from the UCSF Institute for Global Health.
Antiretroviral Therapy in Resource-Poor Settings: Decreasing Barriers to Access and Promoting Adherence
Mukherjee JS, Ivers L, Leandre F, Farmer P, Behforouz H. J Acquir Immune Defic Syndr. 2006 Dec 1;43 Suppl 1:S123-6. Includes commentary from the UCSF Institute for Global Health.
Efficacy of Interventions in Improving Highly Active Antiretroviral Therapy Adherence and HIV-1 RNA Viral Load: A Meta-Analytic Review of Randomized Controlled Trials
Simoni JM, Pearson CR, Pantalone DW, Marks G, Crepaz N. J Acquir Immune Defic Syndr. 2006 Dec 1;43 Suppl 1:S23-35. Includes commentary from the UCSF Institute for Global Health.
Adherence to HAART: A Systematic Review of Developed and Developing Nation Patient-Reported Barriers and Facilitators
Mills EJ, Nachega JB, Bangsberg DR, Singh S, Rachlis B, Wu P, Wilson K, Buchan I, Gill CJ, Cooper C. PLoS Med. 2006 Nov;3(11):e438. Includes commentary from the UCSF Institute for Global Health.
A stress and coping model of medication adherence and viral load in HIV-positive men and women on highly active antiretroviral therapy (HAART).
Weaver KE, Llabre MM, Duran RE, Antoni MH, Ironson G, Penedo FJ, Schneiderman N. Health Psychol. 2005 Jul;24(4):385-92.
Usefulness of therapeutic drug monitoring of antiretrovirals in routine clinical practice.
Duong M, Golzi A, Peytavin G, Piroth L, Froidure M, Grappin M, Buisson M, Kohli E, Chavanet P, Portier H. J HIV Clin Trials. 2004 Jul-Aug;5(4):216-23.
Guidelines and Best Practices
Adherence to Potent Antiretroviral Therapy, in: Guidelines for the Use of Antiretroviral Agents Among HIV-Infected Adults and Adolescents
U.S. Department of Health and Human Services, October 10, 2006.
Online Books and Chapters
Adherence Section: Clinical Manual for Management of the HIV-Infected Adult
AIDS Education and Training Centers National Resource Center, 2006.
Newsletter Articles
Adherence and HIV/AIDS
HRSA Care Action, U.S. Department of Health and Human Services, May 2005.
Antiretroviral Adherence Interventions: A Review of Current Literature and Ongoing Studies
Jane M. Simoni, Pamela A. Frick, David W. Pantalone, Barbara J. Turner. Topics in HIV Medicine, International AIDS Society--USA, November/December 2003.
Hit the Road, Jack (and Jill)
Dawn Averitt. AIDS Care, June 1998. Adherence Tips for Travelers on HIV Medications.
Adhering to Complex Regimens for HIV
Judith G. Rabkin, Margaret A. Chesney. GMHC Treatment Issues, April 1998.
Strategies to Establish and Maintain Optimal Adherence
Margaret A. Chesney. HIV Newsline, June 1997.
Compliance: How Physicians Can Help
Margaret A. Chesney. HIV Newsline, June 1997.
Provider Education and Training
Adherence to Antiretroviral Therapy in Adults: A Guide for Trainers
Horizons/Population Council, International Centre for Reproductive Health, Coast Province General Hospital, Mombasa-Kenya, 2004. [PDF, 1MB]
Clinician Support Tools
ACTG Adherence Baseline Questionnaire
Margaret A. Chesney, Jeannette Ickovics, the AIDS Clinical Trials Group Recruitment, Adherence, and Retention Subcommittee. [PDF, 48K]
ACTG Adherence Follow Up Questionnaire
Margaret A. Chesney, Jeannette Ickovics, the AIDS Clinical Trials Group Recruitment, Adherence, and Retention Subcommittee. [PDF, 48K]
HIV Visual Med Scheduler
An online program from MedActionPlan.com which allows healthcare providers to customize and document treatment regimens for the purpose of improving patient adherence.
Slide Sets
Antiretroviral Resistance Testing in the Management of HIV-Infected Patients
Northwest AETC, August 2006. [PowerPoint, 4.2MB]
Program Management Materials
Adherence Support Program Manual
Jennifer Lorvick and Action Point, April 2002. [PDF, 1040K]
Also see the following appendices:
bullet.gifAppendix A: Literature Review on Adherence in Marginalized Populations [PDF, 146K]
bullet.gifAppendix B: Procedures Manual [PDF, 283K]
bullet.gifAppendix C: Action Point Information and Consent Forms [PDF, 270K]
bullet.gifAppendix D: Client Information System Intake Form [PDF, 392K]
bullet.gifAppendix E: Nursing Intake/Case Conference Form [PDF, 111K]
bullet.gifAppendix F: Blank and Sample Care Plans [PDF, 229K]
bullet.gifAppendix G: Adherence Support Questionnaire [PDF, 168K]
bullet.gifAppendix H: Other Adherence Support Resources [PDF, 141K]
Patient and Community Education
What is Treatment Adherence?
AIDSinfo. HIV and Its Treatment - What You Should Know, Fact Sheet #9, reviewed October 2007. [PDF, 52.16 KB]
Adhering to My HIV Treatment Regimen
AIDSinfo. HIV and Its Treatment - What You Should Know, Fact Sheet #10, page 13, reviewed October 2007. [PDF, 984.49 KB]
Adherence
Aidsmap. An online patient information booklet addressing the support systems, tips, and importance on adhering to your HIV antiretroviral therapy. Last updated May 2005.
The Importance of Adhering to Your Treatment Regimen
Aidsmeds.com, online patient information on adherence. Last updated August 2002.
Links
Aardex
Formerly Aprex, Inc., Aardex offers innovative tools to increase medication adherence and compliance. Site includes a compliance bibliography.
Combo Cards
Pocket-sized information cards with customized information on a person's antiviral regimen, designed to supplement physician-to-patient medication instruction and counseling. A publication of Smart and Strong (POZ Magazine.)
e-pill.com
Offers a range of interesting medication adherence and compliance tools for patients.
iHealth Patient Compliance Portal
Provides links to companies offering a variety of adherence tools.
Pill Planner
Personalized treatment planner on Merck's Crixivan.com website that allow users to create customized, printable adherence tools.
Primer on Pill Swallowing
Online training module from the Baylor International Pediatric AIDS Initiative designed to provide guidelines on teaching children to swallow pills. Videotape also available.
West Portal
Questionnaire software (CASIC Builder) developed for patient audio-computer assisted self-interviews that collects information about a patient's medication regimen for research, surveys, and clinical uses, including adherence studies.