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Interactions of Antiretroviral Drugs: Related Resources
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Related Knowledge Base Chapters
Antiretroviral Drugs Profiles
Laurence Peiperl, Susa Coffey.
Side Effects of Antiretroviral Drugs: Related Resources
Journal Articles
Clinical management of drug interaction with antiretroviral agents
Pau AK. Curr Opin HIV AIDS. 2008 May;3(3):319-24.
Drug-drug interactions with HIV antiretroviral therapy
Clarke A, Stein CR, Townsend ML. US Pharm. 2008;33(4):HS-3-HS-21. April 18, 2008.
Drug interactions with new and investigational antiretrovirals
Brown KC, Paul S, Kashuba AD. Clin Pharmacokinet. 2009;48(4):211-41.
Antiretroviral Therapy and Nutrition Interactions
A repository of journal articles on the topic of ARV medications and their impact upon the nutritional status of HIV-infected individuals, compiled by the United Nations Standing Committee on Nutrition.
Guidelines and Best Practices
Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents
U.S. Department of Health and Human Services Panel on Antiretroviral Guidelines for Adults and Adolescents -- A Working Group of the Office of AIDS Research Advisory Council (OARAC). March 27, 2012. See also slide sets from the AETC National Resource Center.
Managing Drug Interactions in the Treatment of HIV-Related Tuberculosis
U.S. Centers for Disease Control and Prevention. Recommendations for managing drug-drug interactions between antiretroviral medications and rifamycins used for the treatment of tuberculosis.
Criteria for the Medical Care of Adults with HIV Infection: HIV Drug-Drug Interactions
New York State Department of Health AIDS Institute, March 2008. Contains general recommendations and key points to accompany New York state ARV treatment guidelines.
Criteria for the Medical Care of Adults with HIV Infection: Long-Term Complications of Antiretroviral Therapy
New York State Department of Health AIDS Institute, March 2008. Contains general recommendations and key points to accompany New York state ARV treatment guidelines.
Criteria for the Medical Care of Adults with HIV Infection: Drug-Drug Interactions Between ARV Agents, Medications Used in Substance Use Treatment, and Recreational Drugs
New York State Department of Health AIDS Institute, March 2008. Contains general recommendations and key points to accompany New York state ARV treatment guidelines.
Online Books and Chapters
Antiretroviral Medications and Oral Contraceptive Agents Section: Clinical Manual for Management of the HIV-Infected Adult
AIDS Education and Training Centers National Resource Center, 2006.
Drug-Drug Interactions with HIV-Related Medications Section: Clinical Manual for Management of the HIV-Infected Adult
AIDS Education and Training Centers National Resource Center, 2006.
Recreational Drugs and Antiretroviral Therapy Section: Clinical Manual for Management of the HIV-Infected Adult
AIDS Education and Training Centers National Resource Center, 2006.
Provider Education and Training
HIV Drug Interactions Workshop
Cocohoba J, Teague R. San Francisco: UCSF San Francisco Area AIDS Education and Training Center; October 2008. Interactive training activities for clinicians.presented by the Pacific AETC.
Clinician Support Tools
Database of Antiretroviral Drug Interactions
HIV InSite's fully referenced searchable database of interactions involving at least one antiretroviral drug. Provides information regarding effects on drug levels, potential clinical effects, mechanisms of interaction, management tips, and suggested alternative agents.
hiv-druginteractions.org
A Web site from the Liverpool HIV Pharmacology Group of University of Liverpool with includes charts and recent publications about HIV drug interactions.
AIDSInfo Mobile Resources and Tools
AIDSInfo, a service of the U. S. Department of Health and Human Services. AIDSInfo's PDA Tools which include an Antiretroviral Toxicity Tool and Drug Database.
Drug-Drug Interactions in HIV-Infected Patients: A Downloadable Tool for Mobile Devices
A downloadable tool for Palm and Pocket PC/Windows Mobile handheld devices, provided by Clinical Care Options. The tool features an interactive database of nteractions between antiretrovirals and other medications frequently prescribed for HIV-infected patients.
Recreational Drugs and HIV Antivirals: A Guide to Interactions for Clinicians
Urbina A, Faragon J, Kubin C, Castillo A. New York/New Jersey AIDS Education and Training Center; 2008.
Patient and Community Education
Check My Meds
AIDS Meds and POZ. A tool for patients to check for potential interactions among the drugs they are taking..
Drug Interactions
Project Inform. Extensive tables of interactions for HIV-related drugs. Last updated April 2004.
Links
HIV-Specific
AIDSinfo Drug Database
U.S. Department of Health and Human Services (DHHS) project providing information on antiretroviral treatment and drugs that treat or prevent AIDS-related illness.
AIDSmeds.com
Succinct, easy-to-read information on HIV drugs and related issues.
Anti-HIV Compounds Database
Computerized databases containing chemical structures and biological data established at the Division of AIDS (DAIDS) of NIAID to foster developments in the chemotherapy of HIV and opportunistic infections and to serve as an information source.
Database of Antiretroviral Drug Interactions
Search by antiretroviral drug, interacting drug, or interacting drug class. Maintained by HIV InSite.
FDA Office of Special Health Issues, HIV/AIDS Activities
Information on HIV/AIDS drugs, State AIDS Fraud Task Forces, articles, brochures, and useful tables.
hiv-druginteractions.org
Site features information on interactions with each class of antiretroviral drugs. Maintained by the Liverpool HIV Pharmacology Group, University of Liverpool.
HIV Medication Guide
Features information on single- and multiple-HIV drug interactions, a customizable medication chart function, patient drug pamphlets, and more. Available in English and French from JAG enterprises, a clinical pharmacy consultation firm.
Johns Hopkins HIV Guide
An on-line decision support tool designed to assist clinicians in the diagnosis, management and treatment of HIV/AIDS. Requires registration.
NIAID/DAIDS: HIV/AIDS Treatment
An easy-to-read site with a comprehensive overview of the discovery and development of AIDS therapeutics, from the Division of AIDS (DAIDS) of the National Institute of Allergy and Infectious Diseases (NIAID.)
Toronto General Hospital Immunodeficiency Clinic
HIV treatment resources, including drug interactions tables, fact sheets, and other information for health care professionals.
General
Clinical Pharmacology
Up-to-date, peer reviewed, clinically-relevant information on all U.S. drugs, as well as off-label uses and dosages, herbal supplements, nutritional products, and new and investigational drugs. Requires paid subscription.
Cytochrome P450 Drug Interaction Table
Designed as a hypothesis testing, teaching, and reference tool for physicians and researchers interested in drug interactions that are the result of competition for, or effects on the human cytochrome P450 system. Includes links to canned PubMed searches.
FDA Center for Drug Evaluation and Research
(CDER) Reports and information on prescription and over-the-counter drugs, as well as regulatory issues and the drug approval process, public health alerts, and more.
PDR.net
Physicians' Desk Reference online, featuring drug and healthcare information, with separate interfaces for physicians, pharmacists, physician assistants, nurses, and consumers. Registration is required, and is either free or fee-based, depending on the level of access desired.
RxList
Index of information on pharmaceutical products from WebMD. Features search function for looking up drugs by the pill imprint code.
Adverse Event Reporting and Emergencies
American Association of Poison Control Centers
List of poison control centers.
Antiretroviral Pregnancy Registry
Intended to provide an early signal of any major teratogenic effect associated with a prenatal exposure to the products monitored through the registry, a voluntary prospective, exposure-registration, observational study designed to collect and evaluate data on the outcomes of pregnancy exposures to antiretroviral products.
MedWatch
FDA safety information and adverse event reporting program for drugs and other medical products.
U.S. Pharmacopeia Practitioner Reporting
Reporting programs for drug product problems, medication errors, and veterinary medicine.
Vaccine Adverse Event Reporting System
(VAERS) Vaccine surveillance program of the FDA Center for Biologics Evaluation and Research.