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Molecular Insights Into HIV Biology: Related Resources
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Related Knowledge Base Chapters
decorative spacerStructure, Expression, and Regulation of the HIV Genome
Thomas J. Hope, Didier Trono; November 2000.
Journal Articles
decorative spacerCombinatorial RNA-based gene therapy for the treatment of HIV/AIDS
Chung J, DiGiusto DL, Rossi JJ. Expert Opin Biol Ther. 2013 Mar;13(3):437-45.
decorative spacerThe split personality of regulatory T cells in HIV infection
Chevalier MF, Weiss L. Blood. 2013 Jan 3;121(1):29-37.
decorative spacerMacrophages and their relevance in human immunodeficiency virus type I infection
Koppensteiner H, Brack-Werner R, Schindler M. Retrovirology. 2012 Oct 4;9:82.
decorative spacerThe structural biology of HIV-1: mechanistic and therapeutic insights
Engelman A, Cherepanov P. Nat Rev Microbiol. 2012 Mar 16;10(4):279-90.
decorative spacerHIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
Chomont N, El-Far M, Ancuta P, et al. Nat Med. 2009 Jun 21; Epub ahead of print. [PDF]
decorative spacerHIV-1 dynamics: a reappraisal of host and viral factors, as well as methodological issues
Prentice HA, Tang J. Viruses. 2012 Oct 10;4(10):2080-96.
Conference Reports and Proceedings
decorative spacerBasic Science Summary
Mario Stevenson. Topics in Antiviral Medicine, International Antiviral Society-USA, April/May 2013. Highlights of the 20th Conference on Retroviruses and Opportunistic Infections; Atlanta; March 3-6, 2013. [PDF, 124K]
decorative spacerThe Cell Biology of HIV-1 and Other Retroviruses
Eric O. Freed, Andrew J. Mouland. Retrovirology, 2006; 77(3). American Society for Cell Biology Summer Conference; Emory University, Atlanta, GA; July 20-23, 2006. [PDF, 444K]
Presentations, Interviews, and Roundtable Discussions
decorative spacerQuantitative 3D Video Microscopy of HIV Transfer Across T Cell Virological Synapses
Hubner W, McNerney GP, Chen P, et al. Science. 27 March 2009; 323 (5922):1743 - 1747. [Video]
Online Books and Chapters
decorative spacerHIV Sequence Compendium 2012
Kuiken C, Foley B, Marx P, et al. Published by Theoretical Biology and Biophysics, Los Alamos National Laboratory, LA-UR 09-03280.
decorative spacerRetroviruses
John M. Coffin, Stephen H. Hughes, Harold E. Varmus, Cold Spring Harbor Laboratory Press; c1997.
decorative spacerHIV Replication Cycle
National Institute of Allergy and Infectious Disease (NIAID), 2012.
decorative spacerSimplified representation of HIV lifecycle
A graphical overview of HIV infection, starting with the virus interacting with cell surface receptors, then incorporating its genome into the host DNA, and ultimately transforming to the mature infectious form capable of fusing with a new susceptible cell. EMBL. 2009.
Patient and Community Education
decorative spacerBiology of HIV
An overview of basic HIV biology written for a lay audience.
National Institute of Allergy and Infectious Diseases.
decorative spacerMolecular Biology of HIV-1: Regulatory Genes
Gatignol A, McGill University; March 2007. [PDF]
decorative spacerHIV Life Cycle - Animations:
decorative spacerbullet.gifThe Life Cycle of HIV, a Retrovirus
Perry, et al., Microbial Life, First Edition. 2002. [Adobe Flash]
Created by Jim Sullivan.
decorative spacerHIV and Antiretroviral Drugs - Animations:
decorative spacerbullet.gifAnti-HIV Therapy
Bless Castro, PhD, and Laurence Peiperl, MD. The structure, life cycle, and pathogenesis of HIV, and the function of antiretroviral drugs. Animated Flash educational course with audio, produced by GeneEd and HIV InSite. Full running time is 30 minutes, but course may also be viewed in sections.
decorative spacerHIV Databases
The HIV databases contain data on HIV genetic sequences, immunological epitopes, drug resistance-associated mutations, and vaccine trials. The website also gives access to a large number of tools that can be used to analyze these data. Produced by Los Alamos National Laboratory and funded by NIAID.