|  | | Related Knowledge Base Chapters | |  |
| Journal Articles |  |  | HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation Chomont N, El-Far M, Ancuta P, et al. Nat Med. 2009 Jun 21; Epub ahead of print. [PDF] |  |  |  | Follicular dendritic cells activate HIV-1 replication in monocytes/macrophages through a juxtacrine mechanism mediated by P-selectin glycoprotein ligand 1 Ohba K, Ryo A, Dewan Z, et al. J Immunol. 2009 Jul 1; 183(1): 524 - 532. [PDF, 1.0M] |  |  |  | Identification and optimal definition of HIV-derived cytotoxic T lymphocyte (CTL) epitopes for the study of CTL escape, functional avidity and viral evolution Nicole Frahma, Brett Bakera, Christian Brander. Review Article. HIV Molecular Immunology. 2008. [PDF, 460K] |  |
|  |
| Conference Reports and Proceedings |  |  | Basic Science Summary Mario Stevenson. Topics in HIV Medicine, International AIDS Society-USA, May/June 2009. Highlights of the 16th Conference on Retroviruses and Opportunistic Infections, Montreal, Canada, February 8-11, 2009. [PDF, 320K] |  |  |  | Basic Science Summary Mario Stevenson. Topics in HIV Medicine, International AIDS Society-USA, 2008 Mar/Apr. Highlights of the 15th Conference on Retroviruses and Opportunistic Infections, Boston, Massachusetts, February 3-6, 2008 [PDF, 172K] |  |  |  | The Cell Biology of HIV-1 and Other Retroviruses Eric O Freed, Andrew J. Mouland. Retrovirology, 2006; 77(3). American Society for Cell Biology Summer Conference, Emory University, Atlanta, GA, July 20-23, 2006. [PDF, 444K] |  |
|  |
| Presentations, Interviews, and Roundtable Discussions | |  |
| Research Summaries | |  |
| Online Books and Chapters |  |  | HIV Sequence Compendium 2009 Kuiken C, Foley B, Marx P, et al. Published by Theoretical Biology and Biophysics, Los Alamos National Laboratory, LA-UR 09-03280. [PDF] |  |  |  | HIV: Molecular Biology One in a series of lectures for a general virology course run by the Department of Microbiology and Immunology at the University of Rochester Medical Center, Rochester NY. [PDF, 5.8MB] |  |  |  | Retroviruses John M. Coffin, Stephen H. Hughes, Harold E. Varmus, Cold Spring Harbor Laboratory Press; c1997. |  |
|  |
| Newsletter Articles | |  |
| Images |  |  | Lattice maps for immature HIV molecules The 3D computer reconstruction shows the immature Gag lattice of HIV that matures to form the protein shell of the infecious virus. Maps are shown in perspective such that hexamers on the rear surface of the particle appear smaller. The side of the particle toward the viewer lacks ordered Gag. EMBL. 2009. |  |  |  | Simplified representation of HIV lifecycle A graphical overview of HIV infection, starting with the virus interacting with cell surface receptors, then incorporating its genome into the host DNA, and ultimately transforming to the mature infectious form capable of fusing with a new susceptible cell. EMBL. 2009. |  |
|  |
| Patient and Community Education |  |  | Biology of HIV An overview of basic HIV biology written for a lay audience.
National Institute of Allergy and Infectious Diseases. |  |  |  | HIV Life Cycle Animations:
 |  |  | Anti-HIV Therapy Bless Castro, PhD and Laurence Peiperl, MD. The structure, life cycle, and pathogenesis of HIV, and the function of antiretroviral drugs. Animated Flash educational course with audio, produced by GeneEd and HIV InSite. Full running time is 30 minutes, but course may also be viewed in sections.
|
 |  |  | Roche Multimedia, interactive HIV life cycle on Roche's HIV website. Requires Shockwave Flash.
|
|  |
|  |
| Links |  |  | HIV Databases The HIV databases contain data on HIV genetic sequences, immunological epitopes, drug resistance-associated mutations, and vaccine trials. The website also gives access to a large number of tools that can be used to analyze these data. Produced by Los Alamos National Laboratory and funded by NIAID.
|  |
|  |
|