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Global Health Literature Digest
These journal articles are selected from a monthly digest produced by UCSF Global Health Sciences (GHS). This literature digest collection highlights recently published studies of practical relevance for resource-limited settings. These studies of behavioral, policy, and prevention interventions have one or more of the following aims: to reduce sexual or drug-related risk behaviors, to decrease primary or secondary transmission, to improve health service delivery and quality of life, and to improve HIV treatment and treatment adherence. The studies featured have been summarized and put into context by research staff at UCSF Global Health Sciences. In order to access older issues, please see the Archived Issues. Summaries and reviewer commentary are the work of GHS authors and have been published here with the permission of GHS.
December 6, 2013

Comparative efficacy of lamivudine and emtricitabine: a systematic review and meta-analysis of randomized trials
Nutritional status and other baseline predictors of mortality among HIV-infected children initiating antiretroviral therapy in Tanzania
Optimal time for initiating antiretroviral therapy (ART) in HIV-infected, treatment-naive children aged 2 to 5 years old
Efficacy and safety of an extended nevirapine regimen in infants of breastfeeding mothers with HIV-1 infection for prevention of HIV-1 transmission (HPTN 046): 18-month results of a randomized, double-blind, placebo-controlled trial.
September 6, 2013

Impact of generic antiretroviral therapy (ART) and free ART programs on time to initiation of ART at a tertiary HIV care center in Chennai, India
HIV transmission and 24-month survival in a randomize trial of HAART to prevent MTCT during pregnancy and breastfeeding in Botswana
Effect of improved tuberculosis screening and isoniazid preventive therapy on incidence of tuberculosis and death in patients with HIV in clinics in Rio de Janeiro, Brazil: a stepped wedge, cluster-randomised trial
Early time-limited antiretroviral therapy versus deferred therapy in South African infants with HIV: results from the children with HIV early antiretroviral (CHER) randomized trial.
July 31, 2013

Effect of home based HIV counselling and testing intervention in rural South Africa: cluster randomised trial
The effects of home-based HIV counseling and testing on HIV/AIDS stigma among individuals and community leaders in western Kenya: Evidence from a cluster- randomized trial
Decentralising HIV treatment in lower- and middle-income countries
Disengagement from care in a decentralised primary health care antiretroviral treatment programme: cohort study in rural South Africa.
June 17, 2013

Viral suppression after 12 months of antiretroviral therapy in low- and middle-income countries: a systematic review
Integration of antiretroviral therapy services into antenatal care increases treatment initiation during pregnancy: a cohort study
Relationship between mortality and feeding modality among children born to HIV-infected mothers in a research setting: the Kesho Bora Study
Strong effects of home-based voluntary HIV counselling and testing on acceptance and equity: a cluster randomised trial in Zambia
May 13, 2013

Community empowerment among female sex workers is an effective HIV prevention intervention: a systematic review of the peer-reviewed evidence from low- and middle-income countries
Birth diagnosis of HIV infection on infants to reduce infant mortality and monitor for elimination of mother-to-child transmission
The impact of revised PMTCT guidelines: a view from a public sector antiretroviral clinic in Cape Town, South Africa
Improved retention associated with community-based accompaniment for antiretroviral therapy delivery in rural Rwanda
March 27, 2013

Nevirapine versus efavirenz for patients co-infected with HIV and tuberculosis: a randomised non-inferiority trial
Evaluation of harm reduction programs on seroincidence of HIV, hepatitis B and C, and syphilis among intravenous drug users in southwest China
The hidden harm of home-based care: Pulmonary tuberculosis symptoms among children providing home medical care to HIV/AIDS-affected adults in South Africa
Home-based HIV testing and counseling in rural and urban Kenyan communities
February 25, 2013

Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy: a systematic review and meta-analysis
Family economic empowerment and mental health among AIDS-affected children living in AIDS-impacted communities: evidence from a randomised evaluation in southwestern Uganda. J Epidemiol Community Health
Long-term healthcare interruptions among HIV-infected patients in Uganda
Reducing HIV-related stigma in health care settings: A randomized controlled trial in China
January 22, 2013

The Cameroon Mobile Phone SMS (CAMPS) trial: a randomized trial of text messaging versus usual care for adherence to antiretroviral therapy
Integration of HIV care and treatment in primary health care centers and patient retention in central Mozambique: A retrospective cohort study
Pooled individual data analysis of five randomized trials of infant nevirapine prophylaxis to prevent breast-milk HIV-1 transmission
Antiretroviral therapy outcomes among adolescents and youth in rural Zimbabwe
November 9, 2012

Final 192-week efficacy and safety of once-daily darunavir/ritonavir compared with lopinavir/ritonavir in HIV-1-infected treatment-naïve patients in the ARTEMIS trial
Early versus deferred antiretroviral therapy for children older than 1 year infected with HIV (PREDICT): a multicentre, randomised, open-label trial
Changes in Food Insecurity, Nutritional Status, and Physical Health Status After Antiretroviral Therapy Initiation in Rural Uganda
Effectiveness of sport-based HIV prevention interventions: a systematic review of the evidence
September 30, 2012

Provision of services and care for HIV-exposed infants: A comparison of maternal and child health clinic and HIV comprehensive care clinic models
Text messaging to improve attendance at post-operative clinic visits after adult male circumcision for HIV prevention: A randomized controlled trial
Tenofovir in second-line ART in Zambia and South Africa: Collaborative analysis of cohort studies
The immune reconstitution inflammatory syndrome after antiretroviral therapy initiation in patients with tuberculosis: Findings from the SAPiT trial
September 07, 2012

Efficacy and safety of three antiretroviral regimens for initial treatment of HIV-1: a randomized clinical trial in diverse multinational settings
Continuous versus intermittent treatment strategies during primary HIV-1 infection: the randomized ANRS INTERPRIM Trial
Early antiretroviral therapy improves neurodevelopmental outcomes in infants
Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH): a pragmatic, parallel, cluster-randomised trial
August 06, 2012

Nevirapine- Versus Lopinavir/Ritonavir-Based Initial Therapy for HIV-1 Infection among Women in Africa: A Randomized Trial
Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children
Topical microbicides for prevention of sexually transmitted infections
Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals
June 25, 2012

Pregnancy and Infant Outcomes among HIV-Infected Women Taking Long-Term ART with and without Tenofovir in the DART Trial
Integration of HIV and TB Services Results in Improved TB Treatment Outcomes and Earlier Prioritized ART Initiation in a Large Urban HIV Clinic in Uganda
Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya. AIDS Res Treat
NIMH Project Accept (HPTN 043) HIV/AIDS Community Mobilization (CM) to Promote Mobile HIV Voluntary Counseling and Testing (MVCT) in Rural Communities in Northern Thailand: Modifications by Experience
Archived Issues

These studies have been summarized by UCSF Global Health Sciences with support from the Centers for Disease Control and Prevention Global AIDS Program (CDC-GAP). The Digest is then distributed by the U.S. State Department Office of the Global AIDS Coordinator (OGAC) to its personnel based worldwide.