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PrEP in 2011: Results from the iPrEx Study and Discussion of the Public Health Implications

Robert M. Grant, MD, MPH

Grant Colfax, MD

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Dr. Grant, lead author of the iPrEx study, discusses the recently published results that demonstrated partial efficacy of antiretroviral medications as preexposure prophylaxis (PrEP) against HIV acquisition among high-risk HIV uninfected men who have sex with men (MSM) and transgendered women who have sex with men. Dr. Colfax discusses the implications of the iPrEx findings on comprehensive HIV prevention and care services, and considerations involved in implementing PrEP in community settings. Included in their presentation is information on factors associated with greater PrEP effectiveness, as well as on safety and drug resistance. For more information on the study see the iPrEx website.