Slides for Psychoneuroimmunology and HIV: Is There a Mind-Body Connection?

University of California, San Francisco | About UCSF | Search UCSF | UCSF Medical Center

Home > SFGH PHP Grand Rounds > Hecht > Slides

Slides for Psychoneuroimmunology and HIV: Is There a Mind-Body Connection?

Slide Presentation
March 29, 2006
Frederick (Rick) Hecht, MD

Click on slide thumbnails to view full-sized image.

Download Rick Hecht's powerpoint slides

Slide 1.

Psychoneuroimmunlogy and HIV: Is There a Mind-Body Connection?

Slide 1.

James

Slide 2.

What do we do for persons without an indication for HAART?

Slide 3.

Highly Active Antiretroviral Therapy (HAART) limitations

Slide 4.

Stress and Depression Remains Important in HIV

Slide 5.

Depression and HIV Progression

Slide 6.

Depression in the MACS Cohort

Slide 7.

Is depression really associated with more rapid HIV disease progression?

Slide 8.

Depression and CD4 Decline in HERS

Slide 9.

Depression and Mortality in HERS

Slide 10.

Coping in Illness and Health Study

Slide 11.

Stress and HIV Progression

Slide 12.

Stress and HIV Progression

Slide 13.

Follow up of SF Men's Health Study

Slide 14.

Positive Affect Predicts Survival

Slide 15.

Summary of Observational Data on Mood, Stress, and HIV Progression

Slide 16.

Links Between the Neuroendocrine and Immune Systems

Slide 17.

Psychological Stress and the Common Cold

Slide 18.

Positive emotion and susceptibility to the common cold

Slide 19.

Cytokines and Common Cold Symptoms (Doyle, 2006)

Slide 20.

IL-6 is higher in nasal secretions in persons with low positive emotion

Slide 21.

Chronic Stress and Immune Responses to Vaccination

Slide 22.

Influenza Vaccine Responses in Caregivers and Controls

Slide 23.

The Nun's Study

Slide 24.

Model of Stress, Affect, and Progression in HIV

Slide 25.

How Might Stress and Depression Affect HIV Progression?

Slide 26.

HIV Requires Co-Receptors for Cell Entry

Slide 27.

CCR5 Receptor Density is Lower in Persons with Slow HIV Progression

Slide 28.

Norepinephrine Regulates CCR5 Expression

Slide 29.

ANS Activity is Correlated with Viral Load Set-point

Slide 30.

CCR5 Hypothesis

Slide 31.

T-cell Activation and CD4 T-cell loss

Slide 32.

Activation and Stress

Slide 33.

NK Cells and HIV: Cytolytic mechanisms

Slide 34.

NK Cells and HIV: Non-cytolytic mechanisms

Slide 35.

NK Cells and Stress/Depression

Slide 36.

Summary of PNI pathways in HIV

Slide 37.

Yoga and HIV Study

Slide 38.

Psychological Changes from Baseline in HIV Study

Slide 39.

CD4+ T-Cell Changes from Baseline in HIV Study

Slide 40.

MBSR

Slide 41.

MBSR, Brain, and Immune Function

Slide 42.

Increased Left-Sided Anterior Activation

Slide 43.

Greater Responses to Influenza Vaccination

Slide 44.

MBSR in HIV: Robinson Pilot Study

Slide 45.

Staying Well Study

Slide 46.

Design

Slide 47.

Mechanisms of Action

Slide 48.

Summary

Slide 49.