Rilpivirine (Edurant, TMC 278)

Published June 20, 2011; Updated March 2013
Susa Coffey, MD
http://hivinsite.ucsf.edu/InSite?page=ar-02-05
Selected References
1. Cohen CJ, Molina JM, Cahn P, et al; ECHO Study Group; THRIVE Study Group. Efficacy and safety of rilpivirine (TMC278) versus efavirenz at 48 weeks in treatment-naive HIV-1-infected patients: pooled results from the phase 3 double-blind randomized ECHO and THRIVE Trials.J Acquir Immune Defic Syndr. 2012 May 1;60(1):33-42.
3. Rimsky L, Vingerhoets J, Van Eygen V, et al. Genotypic and phenotypic characterization of HIV-1 isolates obtained from patients on rilpivirine therapy experiencing virologic failure in the phase 3 ECHO and THRIVE studies: 48-week analysis. J Acquir Immune Defic Syndr. 2012 Jan 1;59(1):39-46.