January 25, 2001; Updated
|Susa Coffey, MD|
| 17. ||Clarke
Pharmacokinetic interactions of nevirapine and methadone and guidelines for use of nevirapine to treat injection drug users. Clin Infect Dis. 2001 Nov;33(9):1595-7
[PubMed ID: 11568856]
Administration of nevirapine to HIV-infected injection drug users who also receive methadone results in a significant reduction in methadone exposure after 7-10 days of therapy. Many patients require an increase in methadone dose to counteract this effect.