Nevirapine (Viramune)

Published January 25, 2001; Updated October 2016
Susa Coffey, MD
Selected Reference
17. Clarke  SM, Mulcahy  FM, Tjia  J, Reynolds  HE, Gibbons  SE, Barry  MG, Back  DJ.
Pharmacokinetic interactions of nevirapine and methadone and guidelines for use of nevirapine to treat injection drug users. Clin Infect Dis. 2001 Nov;33(9):1595-7
[PubMed ID: 11568856]
Administration of nevirapine to HIV-infected injection drug users who also receive methadone results in a significant reduction in methadone exposure after 7-10 days of therapy. Many patients require an increase in methadone dose to counteract this effect.